The aim of this paper is to investigate the following parabolic system
under homogeneous Dirichlet boundary condition, where
x0(
t):R
+→(0,a) is Hölder continuous, and the constants 0≤α, β <1,
p1,
p2,
q1,
q2,
k1,
k2>0. Under appropriate hypotheses, we first prove the local existence of classical solution by a regularization method. Then we discuss the global existence and blow-up of positive solutions by using a comparison principle. Finally, we give the precise blow-up estimates and the uniform blow-up profiles.